http://localhost:8080/xmlui/handle/123456789/8 2026-05-19T05:36:00Z http://localhost:8080/xmlui/handle/123456789/506 EFFECTS OF SPIRULINA ON POTASSIUM DICHROMATE INDUCED TOXICITIES IN MICE PAUL, SONTUSH RANJAN The present study was performed to observe the effect of spirulina in potassium dichromate induced toxicities in mice. Twenty five healthy mice were randomly divided into five equal groups recognized as T0, T1, T2, T3 and T4 .Group T0was kept as a control group whereas T1was only treated with Potassium dichromate 40mg per 100ml drinking water. Group T2 was treated with Potassium dichromate 40mg and spirulina 70mg per 100ml drinking water. Group T3 was treated with Potassium dichromate 40mg and spirulina 140mg per 100ml drinking water. Group T4 was treated with Potassium dichromate 40mg and spirulina 280 mg per 100ml drinking water. Mice of group T0 (only Potassium dichromate) showed sudden onset of depression, restlessness, anorexia. The body weight gain was minimum (36.38%) not gain in mice of only Potassium dichromate treated T1 group in comparison to control group (T0). On the other hand, other treated group i.e Potassium dichromate plus spirulina treated groups T2, T3, and T4 the not gained body weight was 27.58%, 18.25% and 7.79% respectively, which was higher than only Potassium dichromate T1 group. Reduction of TEC, Hb and PCV values were significant (P˂0.01) in T1 (Potassium dichromate treated) groups. However, in potassium dichromate plus spirulina treated rest group’s reduction of TEC, Hb, and PCV were less than Potassium dichromate treated group. From the study, it can be concluded that Potassium dichromate is harmful to the body showing some toxic signs and also alterations some hematological parameters, where as Spirulina was found to be an effective in reduction of body burden of potassium dichromate. 2016-12-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/505 EFFECTS OF SPIRULINA ON COPPER SULPHATE INDUCED TOXICITIES IN MICE SARKER, SUJAN CHANDRA The present study was performed for finding the effect of spirulina in Copper Sulphate induced toxicities in mice. Twenty five healthy mice were randomly divided into five equal groups recognized as TO, T1, T2, T3 and T4 .Group T0 was kept as a control group whereas T1 was only treated with Copper Sulphate @ 20mg per 100ml drinking water. Group T2 was treated with Copper Sulphate @ 20 mg and Spirulina @ 70mg per 100ml drinking water. Group T3 was treated with Copper Sulphate @ 20 mg and Spirulina @ 140mg per 100ml drinking water. Group T4 was treated with copper Sulphate@ 20 mg and Spirulina @ 280 mg per 100ml drinking water. Mice of group To (only Copper Sulphate) showed sudden onset of depression, restlessness, anorexia. The body weight gain was minimum (54.43%) in mice of only Copper sulphate treated T1 group in comparison to control group (T0). On the other hand, other treated group i.e. Copper Sulphate plus spirulina treated groups T2, T3, and T4 the gaining body weight was 35.29%, 33.83% and 8.82% respectively, which was higher than only Copper Sulphate group T1. Reduction of TEC, Hb and PCV values were significant (P<0.01) in T1 (Copper Sulphate treated) groups. However, in copper plus spirulina treated rest group’s reduction of TEC, Hb, and PCV were less than Copper Sulphate treated group. From the study, it can be concluded that the treatment with spirulina was effective in Copper Sulphate induced toxicities and to restore altered values of Hematological Parameters. 2016-12-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/484 ISOLATION AND IDENTIFICATION OF PATHOGENS FROM PNEUMONIC LUNGS OF SHEEP AND THEIR HISTOPATHOLOGICAL CHANGES IN DIFFERENT AREAS OF SYLHET CITY KHAMA, JAKIA AKTER The important feature of the present study was investigated the pneumonic lungs of sheep and their pathological conditions after slaughtered in different slaughter houses/places of Sylhet city another things isolation and identification of causal agents, antibiotic sensitivity test of were commonly used antibiotics in veterinary practices in our country. During the period from January to June 2016, a total of 300 lungs of slaughtered sheep were examined individually and out of which 80 (15.0%) become affected and lungs were collected for histopathology and bacterial isolation respectively. The gross examination of lungs showed that 40% (120 out of 300 lungs examined) were found positive for pneumonic sheep lungs. The lesions were categorized into (a) hemorrhages 40% (b) congesion 26% (c) hemorrhage with congestion 20% (d) fibrosis of lungs 7% and (e) hepatization in lungs 7%. In histopathological examination, lesions were categorized into (a) bronchopneumonia 26% (acute catarrhal bronchopneumonia 18% and purulent bronchopneumonia 8%), (b) interstitial pneumonia 20%, (c) broncho-interstisial pneumonia 25%, (d) fibrinous pneumonia 22% (e) verminous pneumonia 7%. The highest prevalence of pneumonic lungs was found in bronchopneumonia (26%) and then bronchointerstitial pneumonia (25%) and fibrinous pneumonia (22%). The organisms isolated from the affected lungs were E. coli. (20%), Staphylococcus sp. (25%), Streptococcus sp. 15%, Salmonella sp. 15%, Pasteurella sp. 25%. Finally antibiotics sensitivity test was performed on isolated bacteria. The isolates of Streptococcus sp. and Staphylococcus sp. were highly sensitive to Erythromycin, Ceftriaxone, Nalidixic acid, Penicillin, Chloramphenicol and Gentamycin. On the other hand, antibiotic sensitivity pattern of isolated Escherichia coli and Salmonella sp. were highly sensitive to erythromycin, ceftriaxone, Cefalexine, Nalidixic acid, Gentamycin. The Pasteurella sp. were highly sensitive to Nalidixic acid, Erythromycin, Co-Trimoxazole, Gentamycin, Ceftriaxone, Chloramphenicol & resistant to Penicillin, Ampicillin and Bacitracin. In consideration of the most effective antimicrobial agents against all the tested isolates, Gentamycin, Ceftriaxone, Erythromycin and Nalidixic acid are the drugs of choice for the treatment of pneumonic sheep 2016-12-01T00:00:00Z http://localhost:8080/xmlui/handle/123456789/483 SCORING OF BURSAL LESIONS IN COMMERCIAL CHICKEN INFECTED WITH FIELD IBD VIRUS AT SYLHET REGION AKTAR, MOST. FARZANA The current study was conducted to evaluate the pathogenicity and pathology of infectious bursal disease virus in commercial broiler chickens. A total of 45 bursa of Fabricius were collected from 9 commercial farm of different age (18-29 days) of different areas at Sylhet region. During necropsy both chickens and Bursa of Fabricius (BF) were weighed and examined for gross lesion and processed for histological investigations. Bursal Index and bursal lesion scoring were made to evaluate pathogenicity of the virus. The results showed that the weight of bursa increased effectively according to the body weight. According to the evaluation system 44.44% belongs to the bad category, 22.22% medium, 11.11% average and 22.22% excellent category. In post mortem examination there was severe hemorrhage present on BF, breast and thigh muscle. Hemorrhage was found at the junction between proventriculus and gizzard. Gelatinous and atrophied bursa was also found. Bursal lesion scoring was done based on histopathological investigations, the highest bursal lesion score was 4.6 ±0.40 that indicates bursal atrophy caused by very virulent strain. Bursa were characterized by atrophy, necrosis, fibroplasia, lymphoid depletion, cyst formation and infiltration of inflammatory cells. According to Bursal Index and the observed lesions of BF the virus causing infection of very virulent type. In conclusion, based on the results of the study most of the IBDV infected farms were affected with vvIBDV. However, virus isolation and determination of pathogenicity at laboratory are recommended. 2016-12-01T00:00:00Z