| dc.description.abstract | The efficacy of piperazine citrate (Avipar®) and levamisole (Neotrax®) against naturally
infected ascariasis in indigenous chicken has been studied. A total number of 200 indigenous
chickens were surveyed ranging from 2 months to 1 year of age from different villages of the
Rowmari thana in Kurigram district. On the Basis of faecal egg count, 30 chickens from positive
cases were selected and divided into 3 groups of 10 chickens each. Group A served as the
untreated control, whereas groups B and C were treated with piperazine citrate (Avipar®) and
levamisole (Neotrax®) respectively. The therapeutic efficacy was evaluated through
determination of parasitic prevalence, body weight gain/loss and haematological findings. Fecal
samples were examined to observe the incidence of ascariasis in chicken and average infection
rate was found 86%. The highest infection rate 90% was found in 60-120 days (2-4 months) of
age group. The anthelmintics was significantly increased (p<0.01) the percentage of mean body
weight of chicken of groups B and C as 10.42% and 30% respectively on 28
days after
treatment. But body weight of the control group A, the percentage of mean body weight was
significantly decreased (p<0.01) as 11.36% on 28
th
day of experiment. The reductions of mean
EPG on 14
th
day after treatment were 100% and 100% in the group of chickens of B and
C respectively. There was 100% decrease of mean EPG count following administration of drugs.
Total erythrocyte count (TEC/cu mm), hemoglobin content (Hb gm %) and packed cell volume
(PCV %) were increased significantly (p<0.01 and P<0.05), whereas erythrocyte sedimentation
rate (ESR) and total leukocyte count (TLC 10
th
and 28
th
) were reduced significantly (p<0.05) after
treatment with two patent drugs namely Avipar® and Neotrax®. At the end of the trial
hematological condition of the all chickens were improved. The administration of recommended
doses of two patent drugs namely Avipar® and Neotrax® as anthelmintics suddenly decreased
3
/mm
3
the number of ascaris parasites of indigenous chicken in groups B and C respectively. The
highest reduction number of parasites was recorded on 28
day of drug dosing. From the result of
this research work it is obvious that Avipar® and Neotrax® are highly effective against
ascariasis in chicken. These two drugs are safe and helpful against ascariasis of chicken in
Bangladesh. So,it is concluded that these two anthelmintics can be used against ascariasis in
chicken without any hesitation.
th | en_US |
