| dc.description.abstract | The research work was carried out for a period of 6 months from January to June, 2014 in the
Department of Pharmacology, Sylhet Agricultural University, Sylhet and Sylhet Government
Goat Developing Farm to evaluate the comparative efficacy of herbal drug Annona reticulata
(English name: Custard apple and locally called ‘Ata’) solutions by spraying (7.5%, 15% and
30%) and Ivermectin against ectoparasitic infestation in goat. Twenty five goats of heavily
infested with ectoparasites were selected and randomly divided into 5 equal groups (T0, T1, T2,
T3 and T4) each group consisting of 5 goats. Goats of group T0 was kept as infected control.
Remaining 4 groups i.e. T1, T2, T3 and T4 were treated with Annona reticulata (Ata) spray and
Ivermectin respectively. The efficacy of Ata (Annona reticulate) leaf extract at 7.5 %, 15 % and
30 % were at 62 %, 67 % and 75 % respectively against ectoparasites in goat whereas the
efficacy of Ivermectin was 100%. The pre-treatment (0 day) mean values of TEC (8.20±.035,
8.12±0.018, 8.25±0.020, 8.3±0.014, and 8.15±0.017), PCV (30.60±0.017, 30.49±0.028,
30.55±0.018, 30.7±0.035 and 30.3±0.065) and Hb (6.79±0.032, 7.45±0.020, 7.35±0.020,
7.2±0.029 and 7.25±0.018) were in the control and treated groups of T1, T2, T3 and T4
respectively. On the 28
day of the post-treatment, the mean values of TEC, PCV and HB were
significantly (p<0.01) decreased upto TEC (7.7±0.031), PCV (29.5±0.038) and Hb (6.74±0.023)
in the control groups but were significantly (p<0.01) increased upto TEC (9.38±0.023,
9.88±0.023, 10.43±0.021 and 11.2±0.038), PCV (31.18±0014, 31.33 ±0.024, 31.65 ±0.035 and
31.51±0.030) Hb (8.15±0.018, 8.27±0.023, 8.37±0.024 and 8.69±0.028) in the treated group of
T1, T2, T3 and T4 respectively. The pre-treatment (0 day) mean values of TLC (7.2±0.037,
th
7.28±0.146, 7.58±0.0.085, 7.96±0.170 and 8.46±0.140) and ESR (0.6±0.035, 0.25±0.018,
0.22±0.014, 0.2±0.017 and 0.28±0.0.020) were in the control and treated groups of T1, T2, T3 and
T4 respectively. On the 28
day of the post-treatment, the mean values of TLC were significantly
(p<0.01) increased upto TLC (7.58±0.082) and ESR (0.83±0.015) in the control groups but were
significantly (p<0.01) decreased upto TLC (7.11±0.063, 7.37±0.069, 7.7±0.022 and 8.03±0.129)
and ESR (0.2±0.035, 0.15 ±0.018, 0.13 ±0.011 and 0.15±0.018) in the treated group of T1, T2, T3
and T4 respectively. In this experiment all the goats following Ivermectin injection and Annona
reticulata (Ata) spray remained healthy, no adverse effects and goat’s appetite increased, growth
and coat colour improved rapidly. | en_US |
